ANGPTL4 Antikörper (AA 26-406)

Produktnummer ABIN7144120

Dieses Anti-ANGPTL4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ANGPTL4 in IHC und ELISA. Geeignet für Human.

Kurzübersicht für ANGPTL4 Antikörper (AA 26-406) (ABIN7144120)

Target: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANGPTL4 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Produktdetails anti-ANGPTL4 Antikörper

Bindungsspezifität: AA 26-406

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Angiopoietin-related protein 4 protein (26-406AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ANGPTL4

Target: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Andere Bezeichnung: ANGPTL4

Hintergrund:

Background: Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.

Aliases: Angiopoietin like 4 antibody, Angiopoietin related protein 4 antibody, Angiopoietin-like protein 4 antibody, Angiopoietin-related protein 4 antibody, ANGL4_HUMAN antibody, ANGPT L2 antibody, ANGPT L4 antibody, ANGPTL2 antibody, Angptl4 antibody, ARP4 antibody, Fasting induced adipose factor antibody, FIAF antibody, HARP antibody, Hepatic angiopoietin related protein antibody, Hepatic fibrinogen/angiopoietin related protein antibody, Hepatic fibrinogen/angiopoietin-related protein antibody, HFARP antibody, NL2 antibody, Peroxisome proliferator-activated receptor (PPAR) gamma induced angiopoietin related protein antibody, PGAR antibody, pp1158 antibody, PPARG angiopoietin related protein antibody, PSEC0166 antibody, TGQTL antibody, UNQ171 antibody, Weakly similar to angiopoietin 1 [H.sapiens] antibody

UniProt: Q9BY76

Pathways: Regulation of Lipid Metabolism by PPARalpha