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A2ML1 Antikörper (AA 625-751)

A2ML1 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7143798
  • Target Alle A2ML1 Antikörper anzeigen
    A2ML1 (alpha-2-Macroglobulin-Like 1 (A2ML1))
    Bindungsspezifität
    • 8
    • 7
    • 6
    • 4
    • 3
    • 1
    AA 625-751
    Reaktivität
    • 23
    • 8
    Human
    Wirt
    • 19
    • 4
    Kaninchen
    Klonalität
    • 22
    • 1
    Polyklonal
    Konjugat
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    Dieser A2ML1 Antikörper ist unkonjugiert
    Applikation
    • 19
    • 16
    • 13
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Alpha-2-macroglobulin-like protein 1 protein (625-751AA)
    Isotyp
    IgG
    Top Product
    Discover our top product A2ML1 Primärantikörper
  • Applikationshinweise
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    A2ML1 (alpha-2-Macroglobulin-Like 1 (A2ML1))
    Andere Bezeichnung
    A2ML1 (A2ML1 Produkte)
    Synonyme
    CPAMD9 antikoerper, alpha-2-macroglobulin like 1 antikoerper, A2ML1 antikoerper
    Hintergrund

    Background: Is able to inhibit all four classes of proteinases by a unique \\\'trapping\\\' mechanism. This protein has a peptide stretch, called the \\\'bait region\\\' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase (By similarity). Displays inhibitory activity against chymotrypsin, papain, thermolysin, subtilisin A and, to a lesser extent, elastase but not trypsin. May play an important role during desquamation by inhibiting extracellular proteases.

    Aliases: A2ML1 antibody, CPAMD9Alpha-2-macroglobulin-like protein 1 antibody, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 9 antibody

    UniProt
    A8K2U0
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