AKR1C4 Antikörper (AA 1-323)

Produktnummer ABIN7143695

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch AKR1C4 in ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für AKR1C4 Antikörper (AA 1-323) (ABIN7143695)

Target: AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AKR1C4 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-AKR1C4 Antikörper

Bindungsspezifität: AA 1-323

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Aldo-keto reductase family 1 member C4 protein (1-323AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu AKR1C4

Target: AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))

Andere Bezeichnung: AKR1C4

Hintergrund:

Background: Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone (kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.

Aliases: 3 alpha HSD1 antibody, 3-alpha-HSD1 antibody, 3-alpha-hydroxysteroid dehydrogenase type I antibody, AK1C4_HUMAN antibody, AKR1C4 antibody, Aldo keto reductase family 1 member C4 antibody, Aldo-keto reductase family 1 member C4 antibody, CDR antibody, Chlordecone reductase antibody, DD-4 antibody, DD4 antibody, Dihydrodiol dehydrogenase 4 antibody, HAKRA antibody, HSD3a antibody

UniProt: P17516

Pathways: Steroid Hormone Biosynthesis