AFG3L2 Antikörper (AA 550-759) (Biotin)

Produktnummer ABIN7143583

Dieses Anti-AFG3L2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von AFG3L2 in ELISA. Geeignet für Human.

Kurzübersicht für AFG3L2 Antikörper (AA 550-759) (Biotin) (ABIN7143583)

Target: AFG3L2 (AFG3-Like Protein 2 (AFG3L2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AFG3L2 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-AFG3L2 Antikörper (Biotin)

Bindungsspezifität: AA 550-759

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human AFG3-like protein 2 protein (550-759AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu AFG3L2

Target: AFG3L2 (AFG3-Like Protein 2 (AFG3L2))

Andere Bezeichnung: AFG3L2

Hintergrund:

Background: ATP-dependent protease which is essential for axonal and neuron development. In neurons, mediates degradation of SMDT1/EMRE before its assembly with the uniporter complex, limiting the availability of SMDT1/EMRE for MCU assembly and promoting efficient assembly of gatekeeper subunits with MCU (PubMed:27642048). Required for the maturation of paraplegin (SPG7) after its cleavage by mitochondrial-processing peptidase (MPP), converting it into a proteolytically active mature form (By similarity).

Aliases: AFG3 (ATPase family gene 3, yeast) like 2 antibody, AFG3 ATPase family gene 3 like 2 (yeast) antibody, AFG3 ATPase family gene 3 like 2 antibody, AFG3 like protein 2 antibody, AFG3-like protein 2 antibody, AFG32_HUMAN antibody, AFG3L2 antibody, ATPase family gene 3 like 2 antibody, ATPase family gene 3 yeast antibody, EC 3.4.24.- antibody, FLJ25993 antibody, Paraplegin like protein antibody, Paraplegin-like protein antibody, SCA28 antibody, Spinocerebellar ataxia 28 antibody

UniProt: Q9Y4W6

Pathways: Skeletal Muscle Fiber Development