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ACD Antikörper (AA 328-497)

ACD Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7143546
  • Target Alle ACD Antikörper anzeigen
    ACD (Adrenocortical Dysplasia Homolog (ACD))
    Bindungsspezifität
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 328-497
    Reaktivität
    • 30
    • 12
    • 6
    • 3
    • 3
    • 3
    • 3
    • 1
    Human
    Wirt
    • 24
    • 7
    • 1
    Kaninchen
    Klonalität
    • 27
    • 5
    Polyklonal
    Konjugat
    • 21
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ACD Antikörper ist unkonjugiert
    Applikation
    • 21
    • 9
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Kreuzreaktivität
    Human, Maus
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Adrenocortical dysplasia protein homolog protein (328-497AA)
    Isotyp
    IgG
    Top Product
    Discover our top product ACD Primärantikörper
  • Applikationshinweise
    Recommended dilution: WB:1:500-1:5000,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    ACD (Adrenocortical Dysplasia Homolog (ACD))
    Andere Bezeichnung
    ACD (ACD Produkte)
    Synonyme
    PIP1 antikoerper, PTOP antikoerper, TINT1 antikoerper, TPP1 antikoerper, ACD antikoerper, ACD, shelterin complex subunit and telomerase recruitment factor antikoerper, adrenocortical dysplasia antikoerper, ACD antikoerper, Acd antikoerper
    Hintergrund

    Background: Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends. Without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by recruiting telomerase to telomeres and increasing its processivity. May play a role in organogenesis.

    Aliases: Acd antibody, ACD_HUMAN antibody, Adrenocortical dysplasia homolog antibody, Adrenocortical dysplasia protein homolog antibody, PIP1 antibody, POT1 and TIN2 organizing protein antibody, POT1 and TIN2-interacting protein antibody, TIN2 interacting protein 1 antibody, TINT1 antibody, TPP1 antibody

    UniProt
    Q96AP0
    Pathways
    Telomere Maintenance
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