MOCS3 Antikörper (AA 271-460)

Produktnummer ABIN7143362

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MOCS3 in WB, ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für MOCS3 Antikörper (AA 271-460) (ABIN7143362)

Target: MOCS3 (Molybdenum Cofactor Synthesis 3 (MOCS3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MOCS3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-MOCS3 Antikörper

Bindungsspezifität: AA 271-460

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Adenylyltransferase and sulfurtransferase MOCS3 protein (271-460AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MOCS3

Target: MOCS3 (Molybdenum Cofactor Synthesis 3 (MOCS3))

Andere Bezeichnung: MOCS3

Hintergrund:

Background: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor, NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.

Aliases: Adenylyltransferase MOCS3 antibody, dJ914P20.3 antibody, MGC9252 antibody, MOCS 3 antibody, MOCS3 antibody, MOCS3_HUMAN antibody, Molybdenum cofactor synthesis 3 antibody, Molybdenum cofactor synthesis protein 3 antibody, Molybdopterin synthase sulfurylase antibody, Molybdopterin-synthase sulfurtransferase antibody, MPT synthase sulfurylase antibody, Sulfur carrier protein MOCS2A adenylyltransferase antibody, Sulfur carrier protein MOCS2A sulfurtransferase antibody, Sulfurtransferase MOCS3 antibody, UBA 4 antibody, UBA4 ubiquitin activating enzyme E1 homolog antibody, UBA4 antibody

UniProt: O95396