AKAP1 Antikörper (AA 413-662)

Produktnummer ABIN7142902

Dieses Anti-AKAP1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von AKAP1 in WB, IHC und ELISA. Geeignet für Human.

Kurzübersicht für AKAP1 Antikörper (AA 413-662) (ABIN7142902)

Target: AKAP1 (A Kinase (PRKA) Anchor Protein 1 (AKAP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AKAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-AKAP1 Antikörper

Bindungsspezifität: AA 413-662

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human A-kinase anchor protein 10, mitochondrial protein (413-662AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu AKAP1

Target: AKAP1 (A Kinase (PRKA) Anchor Protein 1 (AKAP1))

Andere Bezeichnung: AKAP1

Hintergrund:

Background: Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling multiprotein complexes. With its RGS domain, it could lead to the interaction to G-alpha proteins, providing a link between the signaling machinery and the downstream kinase (By similarity).

Aliases: AKAP10A-kinase anchor protein 10 antibody, mitochondrial antibody, AKAP-10 antibody, Dual specificity A kinase-anchoring protein 2 antibody, D-AKAP-2 antibody, Protein kinase A-anchoring protein 10 antibody, PRKA10 antibody

UniProt: O43572

Pathways: Synaptic Membrane