RPL13A Antikörper (AA 63-190) (HRP)

Produktnummer ABIN7142747

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RPL13A in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für RPL13A Antikörper (AA 63-190) (HRP) (ABIN7142747)

Target: RPL13A (Ribosomal Protein L13a (RPL13A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPL13A Antikörper ist konjugiert mit HRP

Applikation: ELISA

Produktdetails anti-RPL13A Antikörper (HRP)

Bindungsspezifität: AA 63-190

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human 60S ribosomal protein L13a protein (63-190AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu RPL13A

Target: RPL13A (Ribosomal Protein L13a (RPL13A))

Andere Bezeichnung: RPL13A

Hintergrund:

Background: Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3\'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site and blocks the recruitment of the 43S ribosomal complex. Involved in methylation of rRNA.

Aliases: RPL13A antibody, 60S ribosomal protein L13a antibody, 23 kDa highly basic protein antibody, Large ribosomal subunit protein uL13 antibody

UniProt: P40429