Perfringolysin O (Pfo) (AA 29-500) Antikörper

Produktnummer ABIN7141088

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Perfringolysin O (Pfo) in ELISA und WB. Es zeigt Reaktivität gegenüber Proben von Clostridium perfringens.

Kurzübersicht für Perfringolysin O (Pfo) (AA 29-500) Antikörper (ABIN7141088)

Target: Perfringolysin O (Pfo)

Reaktivität: Clostridium perfringens

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails

Bindungsspezifität: AA 29-500

Verwendungszweck: pfo Antibody

Aufreinigung: Protein G purified

Reinheit: >95 %

Immunogen: Recombinant Clostridium perfringens Perfringolysin O protein (29-500AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Antigendetails

Target: Perfringolysin O (Pfo)

Andere Bezeichnung: pfo

Hintergrund:

Background: Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein assembles into a pre-pore complex. A conformation change leads to insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host cell membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation.

Aliases: pfo antibody, pfoA antibody, pfoR antibody, CPE0163 antibody, Perfringolysin O antibody, Theta-toxin antibody, Thiol-activated cytolysin antibody

UniProt: P0C2E9