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KRT17 Antikörper (AA 1-441) (HRP)

KRT17 Reaktivität: Rind (Kuh) ELISA Wirt: Kaninchen Polyclonal HRP
Produktnummer ABIN7346591
  • Target Alle KRT17 Antikörper anzeigen
    KRT17 (Keratin 17 (KRT17))
    Bindungsspezifität
    • 15
    • 15
    • 11
    • 9
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1-441
    Reaktivität
    • 129
    • 48
    • 30
    • 18
    • 13
    • 11
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Rind (Kuh)
    Wirt
    • 102
    • 37
    • 1
    Kaninchen
    Klonalität
    • 91
    • 48
    • 1
    Polyklonal
    Konjugat
    • 62
    • 14
    • 8
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KRT17 Antikörper ist konjugiert mit HRP
    Applikation
    • 100
    • 45
    • 36
    • 30
    • 27
    • 26
    • 21
    • 18
    • 17
    • 16
    • 9
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    ELISA
    Kreuzreaktivität
    Rind (Kuh)
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Bovine Keratin, type I cytoskeletal 17 protein (1-441AA)
    Isotyp
    IgG
    Top Product
    Discover our top product KRT17 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    KRT17 (Keratin 17 (KRT17))
    Andere Bezeichnung
    KRT17 (KRT17 Produkte)
    Hintergrund

    Background: Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair. Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state. Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway. Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial \"stem cells\". Acts as a promoter of epithelial proliferation by acting a regulator of immune response in skin: promotes Th1/Th17-dominated immune environment contributing to the development of basaloid skin tumors. May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation.

    Aliases: KRT17 antibody, Keratin antibody, type I cytoskeletal 17 antibody, Cytokeratin-17 antibody, CK-17 antibody, Keratin-17 antibody, K17 antibody

    UniProt
    A1L595
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