PtxA (AA 35-269) Antikörper

Produktnummer ABIN7140770

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PtxA in ELISA und WB. Es zeigt Reaktivität gegenüber Proben von Bordetella pertussis.

Kurzübersicht für PtxA (AA 35-269) Antikörper (ABIN7140770)

Target: PtxA

Reaktivität: Bordetella pertussis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails

Bindungsspezifität: AA 35-269

Verwendungszweck: ptxA Antibody

Aufreinigung: Protein G purified

Reinheit: >95 %

Immunogen: Recombinant Bordetella pertussis Pertussis toxin subunit 1 protein (35-269AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Antigendetails

Target: PtxA

Hintergrund:

Background: S1 is an NAD-dependent ADP-ribosyltransferase, which plays a crucial role in the pathogenesis of B.pertussis causing disruption of normal host cellular regulation. It catalyzes the ADP-ribosylation of a cysteine in the alpha subunit of host heterotrimeric G proteins. In the absence of G proteins it also catalyzes the cleavage of NAD+ into ADP-ribose and nicotinamide. It irreversibly uncouples the G-alpha GTP-binding proteins from their membrane receptors.

Aliases: ptxA antibody, BP3783 antibody, Pertussis toxin subunit 1 antibody, PTX S1 antibody, Islet-activating protein S1 antibody, IAP S1 antibody, NAD-dependent ADP-ribosyltransferase antibody, EC 2.4.2.- antibody

UniProt: P04977