CBR1 Antikörper
Kurzübersicht für CBR1 Antikörper (ABIN7140302)
Target
Alle CBR1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Human
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Aufreinigung
- Affinity purified
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Immunogen
- Purified recombinant human CBR1 protein fragments expressed in E.coli
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Isotyp
- IgG1, IgG1 kappa
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Applikationshinweise
- Recommended dilution:WB:1:500-1:5000,ICC:1:50-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified mouse monoclonal in PBS( pH 7.4)containing with 0.2 % sodium azide,50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CBR1 (Carbonyl Reductase 1 (CBR1))
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Andere Bezeichnung
- CBR1
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Hintergrund
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Background: NADPH-dependent reductase with broad substrate specificity.Catalyzes the reduction of a wide variety of carbonyl compounds including quinones,prostaglandins, menadione,plus various xenobiotics.Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha.Can bind glutathione,which explains its higher affinity for glutathione-conjugated substrates.Catalyzes the reduction of S-nitrosoglutathione.
Aliases: 15 hydroxyprostaglandin dehydrogenase [NADP+], 15-hydroxyprostaglandin dehydrogenase [NADP+], Carbonyl reductase [NADPH] 1, Carbonyl Reductase 1, CBR 1, CBR1, CBR1_HUMAN, CRN, NADPH dependent carbonyl reductase 1, NADPH-dependent carbonyl reductase 1,
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UniProt
- P16152
Target
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