RTN4RL2 Antikörper (AA 355-372)

Produktnummer ABIN7140114

Der Kaninchen Polyklonal Anti-RTN4RL2-Antikörper wurde für WB, ELISA, IHC und IF validiert. Er ist geeignet, RTN4RL2 in Proben von Human zu detektieren.

Kurzübersicht für RTN4RL2 Antikörper (AA 355-372) (ABIN7140114)

Target: RTN4RL2 (Reticulon 4 Receptor-Like 2 (RTN4RL2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RTN4RL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-RTN4RL2 Antikörper

Bindungsspezifität: AA 355-372

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Peptide sequence from Human Reticulon-4 receptor-like 2 protein (355-372AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu RTN4RL2

Target: RTN4RL2 (Reticulon 4 Receptor-Like 2 (RTN4RL2))

Andere Bezeichnung: RTN4RL2

Hintergrund:

Background: Cell surface receptor that plays a functionally redundant role in the inhibition of neurite outgrowth mediated by MAG (By similarity). Plays a functionally redundant role in postnatal brain development. Contributes to normal axon migration across the brain midline and normal formation of the corpus callosum. Does not seem to play a significant role in regulating axon regeneration in the adult central nervous system. Protects motoneurons against apoptosis, protection against apoptosis is probably mediated by MAG (By similarity). Like other family members, plays a role in restricting the number dendritic spines and the number of synapses that are formed during brain development (PubMed: 22325200). Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton (PubMed: 22325200).

Aliases: RTN4RL2 antibody, NGRH1 antibody, NGRL3 antibody, Reticulon-4 receptor-like 2 antibody, Nogo receptor-like 3 antibody, Nogo-66 receptor homolog 1 antibody, Nogo-66 receptor-related protein 2 antibody, NgR2 antibody

UniProt: Q86UN3