OPRK1 Antikörper (AA 31-50) (Biotin)

Produktnummer ABIN7139900

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch OPRK1 in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für OPRK1 Antikörper (AA 31-50) (Biotin) (ABIN7139900)

Target: OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OPRK1 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-OPRK1 Antikörper (Biotin)

Bindungsspezifität: AA 31-50

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Peptide sequence from Human Kappa-type opioid receptor protein (31-50AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu OPRK1

Target: OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

Andere Bezeichnung: OPRK1

Hintergrund:

Background: G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain. Plays a role in mediating reduced physical activity upon treatment with synthetic opioids. Plays a role in the regulation of salivation in response to synthetic opioids. May play a role in arousal and regulation of autonomic and neuroendocrine functions.

Aliases: K-OR-1 antibody, Kappa opioid receptor antibody, Kappa type opioid receptor antibody, Kappa-type opioid receptor antibody, KOR 1 antibody, KOR antibody, KOR-1 antibody, Opiate receptor kappa 1 antibody, Opiate receptor, kappa 1 antibody, Opioid receptor, kappa 1 antibody, OPRK 1 antibody, OPRK antibody, OPRK_HUMAN antibody, OPRK1 antibody, Oprk2 antibody, R21 antibody

UniProt: P41145