AMOTL2 Antikörper (AA 718-737)
Kurzübersicht für AMOTL2 Antikörper (AA 718-737) (ABIN7139725)
Target
Alle AMOTL2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 718-737
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Kreuzreaktivität
- Human
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Aufreinigung
- Antigen Affinity Purified
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Immunogen
- Peptide sequence from Human Angiomotin-like protein 2 protein (718-737AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: WB:1:1000-1:5000,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- AMOTL2 (Angiomotin Like 2 (AMOTL2))
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Andere Bezeichnung
- AMOTL2
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Hintergrund
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Background: Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. Participates in angiogenesis. May play a role in the polarity, proliferation and migration of endothelial cells. Selectively promotes FGF-induced MAPK activation through SRC.
Aliases: AMOL2_HUMAN antibody, Amotl2 antibody, angiomotin like 2 antibody, Angiomotin-like protein 2 antibody, KIAA0989 antibody, LCCP antibody, Leman coiled coil protein antibody, Leman coiled-coil protein antibody
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UniProt
- Q9Y2J4
Target
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