Caveolin 2 Antikörper (pTyr27)

Produktnummer ABIN7138965

Der Kaninchen Polyklonal Anti-Caveolin 2-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, Caveolin 2 in Proben von Human zu detektieren.

Kurzübersicht für Caveolin 2 Antikörper (pTyr27) (ABIN7138965)

Target: Caveolin 2 (CAV2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caveolin 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Caveolin 2 Antikörper

Bindungsspezifität: pTyr27

Kreuzreaktivität: Human

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of tyrosine 27 (L-E-Y(p)-A-D) derived from Human Caveolin 2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:1000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Caveolin 2

Target: Caveolin 2 (CAV2)

Andere Bezeichnung: CAV2

Hintergrund:

Background:

The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Two transcript variants encoding distinct isoforms have been identified for this gene. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by one transcript.

Scherer P.E., Proc. Natl. Acad. Sci. U.S.A. 93:131-135(1996).
Scherer P.E., J. Biol. Chem. 272:29337-29346(1997).
Engelman J.A., FEBS Lett. 448:221-230(1999).

Aliases: CAV antibody, CAV2 antibody, CAV2_HUMAN antibody, Caveolae protein 20 kD antibody, Caveolin 2 antibody, Caveolin 2 isoform a and b antibody, Caveolin-2 antibody, MGC12294 antibody, OTTHUMP00000025032 antibody, OTTHUMP00000195982 antibody

UniProt: P51636

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development