Claudin 5 Antikörper (pTyr217)

Produktnummer ABIN7138958

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Claudin 5 in IHC und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Claudin 5 Antikörper (pTyr217) (ABIN7138958)

Target: Claudin 5 (CLDN5)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Claudin 5 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Produktdetails anti-Claudin 5 Antikörper

Bindungsspezifität: pTyr217

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of tyrosine 217 (K-K-N-Y(p)-V) derived from Human Claudin 5.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC:1:50-1:100,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Claudin 5

Target: Claudin 5 (CLDN5)

Andere Bezeichnung: CLDN5

Hintergrund:

Background:

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome.

Sirotkin H., Genomics 42:245-251(1997).
Collins J.E., Genome Biol. 5:RESEARCH84.1-RESEARCH84.11(2004).
The MGC Project Team, Genome Res. 14:2121-2127(2004).

Aliases: Androgen withdrawal and apoptosis induced protein RVP1 like antibody, AWAL antibody, BEC 1 antibody, BEC1 antibody, Claudin 5 (transmembrane protein deleted in velocardiofacial syndrome) antibody, Claudin-5 antibody, Claudin5 antibody, CLD5_HUMAN antibody, CLDN 5 antibody, Cldn5 antibody, CPETR L1 antibody, CPETRL 1 antibody, CPETRL1 antibody, TMDVCF antibody, TMVCF antibody, Transmembrane protein deleted in VCFS antibody, Transmembrane protein deleted in velocardiofacial syndrome antibody

UniProt: O00501

Pathways: Hepatitis C