CSNK2A1/CK II alpha Antikörper (pSer362, pThr360)

Produktnummer ABIN7138896

Der Kaninchen Polyklonal Anti-CSNK2A1/CK II alpha-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, CSNK2A1/CK II alpha in Proben von Human zu detektieren.

Kurzübersicht für CSNK2A1/CK II alpha Antikörper (pSer362, pThr360) (ABIN7138896)

Target: CSNK2A1/CK II alpha (CSNK2A1) (Casein Kinase 2 alpha 1 (CSNK2A1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CSNK2A1/CK II alpha Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CSNK2A1/CK II alpha Antikörper

Bindungsspezifität: pSer362, pThr360

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of threonine360/serine 362 (V-P-T(p)-P-S(p)-P-L) derived from Human CK2a.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:1000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CSNK2A1/CK II alpha

Target: CSNK2A1/CK II alpha (CSNK2A1) (Casein Kinase 2 alpha 1 (CSNK2A1))

Andere Bezeichnung: CSNK2A1

Hintergrund:

Background: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The a and a' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53/TP53 following UV irradiation.

Keller D.M., Zeng X., et al., Mol. Cell 7:283-292(2001)
Keller D.M., Lu H. et al., J. Biol. Chem. 277:50206-50213(2002)
Trembley J.H., Tatsumi S., et al., Mol. Cell. Biol. 25:1446-1457(2005)
Niefind K., Guerra B., et al., Acta Crystallogr. D 56:1680-1684(2000)

Aliases: Casein kinase 2 alpha 1 polypeptide antibody, Casein kinase II alpha 1 antibody, Casein kinase II alpha 1 subunit antibody, Casein kinase II alpha subunit antibody, Casein kinase II subunit alpha antibody, CK II alpha antibody, CK II antibody, CK2 alpha antibody, CK2 catalytic subunit alpha antibody, CK2A1 antibody, CKII antibody, CKIIalpha antibody, CSK21_HUMAN antibody, CSNK2A1 antibody

UniProt: P68400

Pathways: SARS-CoV-2 Protein Interaktom