SYT1/SYT2 (pThr199), (pThr202) Antikörper

Produktnummer ABIN7138799

Produktdetails

Target: SYT1/SYT2

Bindungsspezifität: pThr199, pThr202

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of threonine 202/199 (R-K-T(p)-L-N) derived from Human Synaptotagmin 1/2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF:1:100-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Antigendetails

Target: SYT1/SYT2

Hintergrund:

Background:

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse

Gustavsson N, et al. Proc Natl Acad Sci U S A. 2008 Mar 11, 105(10):3992-7.
Cnops L, et al. Cereb Cortex. 2008 May, 18(5):1221-31.
Lynch KL, et al. Mol Biol Cell. 2007 Dec, 18(12):4957-68.

Aliases: DKFZp781D2042 antibody, FLJ42519 antibody, p65 antibody, SVP65 antibody, Synaptotagmin 2 antibody, Synaptotagmin I antibody, Synaptotagmin II antibody, Synaptotagmin-1 antibody, SYT antibody, Syt1 antibody, SYT1_HUMAN antibody, Syt2 antibody, SytI antibody

UniProt: P21579