NOS1 Antikörper (pSer852)

Produktnummer ABIN7138716

Der Kaninchen Polyklonal Anti-NOS1 Antikörper wurde für WB und ELISA validiert. Er ist geeignet, NOS1 in Proben von Human zu detektieren.

Kurzübersicht für NOS1 Antikörper (pSer852) (ABIN7138716)

Target: NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NOS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-NOS1 Antikörper

Bindungsspezifität: pSer852

Verwendungszweck: Phospho-NOS1 (Ser852) Antibody

Kreuzreaktivität: Maus, Ratte

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of serine 852(F-N-S(p)-V-S) derived from Human n-NOS .

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu NOS1

Target: NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))

Andere Bezeichnung: NOS1

Hintergrund:

Background:

Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.

Capettini LS, et al. (2011) DBr J Pharmacol 164, 1738-48
Ferreira JM, Burnett AL, Rameau GA (2011) J Neurosci 31, 1991-9
Chaudhury A, Rao YM, Goyal RK (2008) Am J Physiol Gastrointest Liver Physiol 295, G442-51

Aliases: 2310005C01Rik antibody, BNOS antibody, Constitutive NOS antibody, EC 1.14.13.39 antibody, IHPS 1 antibody, IHPS1 antibody, N-NOS antibody, NC-NOS antibody, neuronal Nitric Oxide Synthase antibody, Neuronal NOS antibody, Nitric oxide synthase , neuronal, included antibody, Nitric oxide synthase 1 (neuronal) antibody, Nitric oxide synthase 1 antibody, Nitric oxide synthase, brain antibody, Nitric oxide synthase, penile neuronal, included antibody, NNOS antibody, NO antibody, NOS 1 antibody, NOS antibody, NOS type I antibody, NOS-I antibody, NOS1 antibody, NOS1_HUMAN antibody, Peptidyl-cysteine S-nitrosylase NOS1 antibody

UniProt: P29475

Pathways: Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction