Ataxin 1 Antikörper (pSer776)
Kurzübersicht für Ataxin 1 Antikörper (pSer776) (ABIN7138699)
Target
Alle Ataxin 1 (ATXN1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer776
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Kreuzreaktivität
- Human, Maus
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Aufreinigung
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
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Immunogen
- Peptide sequence around phosphorylation site of Serine 776(R-W-S(p)-A-P) derived from Human Ataxin 1.
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Isotyp
- IgG
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Applikationshinweise
- WB:1:500-1:1000,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Ataxin 1 (ATXN1)
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Andere Bezeichnung
- ATXN1
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Hintergrund
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Background: Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. The expansion of the polyglutamine tract may alter this function.
Aliases: alternative ataxin1 antibody, Ataxin-1 antibody, ATX1 antibody, ATX1_HUMAN antibody, Atxn1 antibody, D6S504E antibody, OTTHUMP00000016065 antibody, SCA1 antibody, Spinocerebellar ataxia type 1 protein antibody
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UniProt
- P54253
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Pathways
- Synaptic Membrane
Target
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