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KRT8 Antikörper (pSer74)

Name: KRT8 Antikörper (pSer74)
Brand: antibodies-online
SKU: ABIN7138693
Price: 475.2 EUR
Availability: InStock

KRT8 Reaktivität: Human WB, IF, ELISA Wirt: Kaninchen Polyclonal unconjugated

Western blot analysis of extracts from 293 cells, treated with calf intestinal phosphatase (CIP), using Keratin 8 (Phospho-Ser74) Antibody. (KRT8 Antikörper (pSer74))

Western blot analysis of extracts from HepG2 cells untreated or treated with EGF using Keratin 8(Phospho-Ser74) Antibody. (KRT8 Antikörper (pSer74))

Immunofluorescence staining of methanol-fixed Hela cells using Keratin 8(Phospho-Ser74) Antibody. (KRT8 Antikörper (pSer74))

3 Abbildungen

Produktnummer ABIN7138693

Datenblatt (PDF)

Target Alle KRT8 Antikörper anzeigen

KRT8 (Keratin 8 (KRT8))
Bindungsspezifität
23

16

13

11

8

6

6

6

5

5

4

4

4

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer74
Reaktivität
255

80

76

33

33

31

30

16

14

10

8

5

4

3

2

1

1

1
Human
Wirt
137

126

3
Kaninchen
Passende Sekundärantikörper
Klonalität
134

129

1
Polyklonal
Konjugat
147

21

16

9

4

4

4

4

4

4

3

3

3

3

3

3

3

3

3

3

3

3

2

2

2

1

1

1

1

1

1

1
Dieser KRT8 Antikörper ist unkonjugiert
Applikation
173

103

100

80

69

46

41

40

30

29

24

19

5

5

4

4

2

2

2

1

1
Western Blotting (WB), Immunofluorescence (IF), ELISA

Kreuzreaktivität

Human

Aufreinigung

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen

Peptide sequence around phosphorylation site of serine 74 (L-L-S(p)-P-L) derived from Human Keratin 8 (CK8).

Isotyp

IgG

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anti-Keratin 8 (KRT8) (N-Term) antibody
KRT8 Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Saccharomyces cerevisiae WB, IHC Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB:1:500-1:1000, IF:1:100-1:200,

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C,-80 °C

Informationen zur Lagerung

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target

KRT8 (Keratin 8 (KRT8))

Andere Bezeichnung

KRT8 (KRT8 Produkte)

Hintergrund

Background:
Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.

Nakamichi I, et al. (2002) Mol Biol Cell, 13(10): 3441-3451.
Prochasson P, et al. (2002) Nucleic Acids Res, 30(15): 3312-3322.
Pankov R, et al. (1994) Proc Natl Acad Sci U S A, 91(3): 873-877.
Thorey IS, et al. (1993) Mol Cell Biol, 13(11): 6742-6751
Aliases: CARD2 antibody, CK 8 antibody, CK-8 antibody, CK8 antibody, CYK8 antibody, CYKER antibody, Cytokeratin endo A antibody, Cytokeratin-8 antibody, DreK8 antibody, EndoA antibody, K2C8 antibody, K2C8_HUMAN antibody, K8 antibody, Keratin 8 antibody, Keratin type II cytoskeletal 8 antibody, Keratin, type II cytoskeletal 8 antibody, Keratin-8 antibody, KO antibody, Krt 2.8 antibody, KRT8 antibody, MGC118110 antibody, MGC174782 antibody, MGC53564 antibody, MGC85764 antibody, sb:cb186 antibody, Type-II keratin Kb8 antibody

UniProt

P05787