MDC1 Antikörper (pSer513)

Produktnummer ABIN7138640

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MDC1 in ELISA und IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für MDC1 Antikörper (pSer513) (ABIN7138640)

Target: MDC1 (Mdc1 (MDC1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MDC1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-MDC1 Antikörper

Bindungsspezifität: pSer513

Verwendungszweck: Phospho-MDC1 (Ser513) Antibody

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of Serine 513(E-R-S(p)-Q-A) derived from Human MDC1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MDC1

Target: MDC1 (Mdc1 (MDC1))

Andere Bezeichnung: MDC1

Hintergrund:

Background:

The MDC1 protein contains a forkhead homology-associated (FHA) domain and 2 BRCA1 (MIM 113705) C-terminal motifs (BRCTs) and is required for the intra-S-phase DNA damage checkpoint.

Nagase T., DNA Res. 3:17-24(1996).
Shiina T., Genetics 173:1555-1570(2006).
Mungall A.J., Nature 425:805-811(2003).

Aliases: Homologue to Drosophila photoreceptor protein calphotin antibody, MDC 1 antibody, Mdc1 antibody, MDC1_HUMAN antibody, Mediation of DNA damage checkpoint 1 antibody, Mediator of DNA damage checkpoint 1 antibody, Mediator of DNA damage checkpoint protein 1 antibody, NFBD 1 antibody, NFBD1 antibody, Nuclear factor with BRCT domains 1 antibody, Nuclear Factor with BRCT Domains Protein 1 antibody

UniProt: Q14676