CXCR2 Antikörper (pSer347)
Kurzübersicht für CXCR2 Antikörper (pSer347) (ABIN7138568)
Target
Alle CXCR2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer347
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Kreuzreaktivität
- Human, Maus
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Aufreinigung
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
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Immunogen
- Peptide sequence around phosphorylation site of Serine 347(R-P-S(p)-F-V) derived from Human IL-8R beta/CDw128 beta
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Isotyp
- IgG
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Applikationshinweise
- WB:1:500-1:1000,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))
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Andere Bezeichnung
- CXCR2
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Hintergrund
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Background: Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
Aliases: C-X-C chemokine receptor type 2 antibody, CD 182 antibody, CD182 antibody, CD182 antigen antibody, CDw128b antibody, Chemokine (CXC) receptor 2 antibody, CMKAR2 antibody, CXC-R2 antibody, CXCR 2 antibody, CXCR-2 antibody, CXCR2 antibody, CXCR2_HUMAN antibody, GRO/MGSA receptor antibody, High affinity interleukin-8 receptor B antibody, IL 8 receptor type 2 antibody, IL 8R B antibody, IL-8 receptor type 2 antibody, IL-8R B antibody, IL8 RB antibody, IL8 receptor type 2 antibody, IL8R B antibody, IL8R2 antibody, IL8RA antibody, Interleukin 8 Receptor B antibody, Interleukin 8 receptor, beta antibody, Interleukin 8 receptor, type 2 antibody
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UniProt
- P25025
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Pathways
- cAMP Metabolic Process
Target
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