beta 2 Adrenergic Receptor Antikörper (pSer346)

Produktnummer ABIN7138567

Produktdetails anti-beta 2 Adrenergic Receptor Antikörper

Target: beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))

Bindungsspezifität: pSer346

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser beta 2 Adrenergic Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Human

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of serine 346 (R-S-S(p)-L-K) derived from Human Adrenergic Receptor beta2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:1000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu beta 2 Adrenergic Receptor

Target: beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))

Andere Bezeichnung: ADRB2 (ADRB2 Produkte)

Hintergrund:

Background:

Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.

Gao S, Malbon C, Wang HY (2014) J Mol Signal 9, 3
24690384 Curated Info
Vistein R, Puthenveedu MA (2013) Proc Natl Acad Sci U S A 110, 15289-94
Gimenez LE, et al. (2012) J Biol Chem 287, 9028-40

Aliases: ADRB2 antibody, ADRB2_HUMAN antibody, ADRB2R antibody, ADRBR antibody, Adrenergic beta 2 receptor surface antibody, Adrenoceptor beta 2 surface antibody, B2AR antibody, BAR antibody, beta 2 adrenoceptor antibody, Beta 2 adrenoreceptor antibody, Beta-2 adrenergic receptor antibody, Beta-2 adrenoceptor antibody, Beta-2 adrenoreceptor antibody, BETA2AR antibody, Catecholamine receptor antibody, OTTHUMP00000160386 antibody

UniProt: P07550

Pathways: cAMP Metabolic Process, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation