MYL9 Antikörper (pSer15)

Produktnummer ABIN7138433

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MYL9 in WB, ELISA und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für MYL9 Antikörper (pSer15) (ABIN7138433)

Target: MYL9 (Myosin Regulatory Light Polypeptide 9 (MYL9))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYL9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-MYL9 Antikörper

Bindungsspezifität: pSer15

Kreuzreaktivität: Human

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of serine 15 (A-N-S(p)-N-V) derived from Human MLC2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:1000, IF:1:100-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MYL9

Target: MYL9 (Myosin Regulatory Light Polypeptide 9 (MYL9))

Andere Bezeichnung: MYL9

Hintergrund:

Background:

 Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion.

 

1) Xia, Y. et al. c-Jun downregulation by HDAC3-dependent transcriptional repression promotes osmotic stress-induced cell apoptosis. Mol. Cell 25, 219–232 (2007).

2)Vander Heiden, M. G. et al. Evidence for an alternative glycolytic pathway in rapidly proliferating cells. Science 329, 1492–1499 (2010).

3) Fang, D. et al. Phosphorylation of beta-catenin by AKT promotes beta-catenin transcriptional activity. J. Biol. Chem. 282, 11221–11229 (2007).

Aliases: 20 kDa myosin light chain antibody; Human 20kDa myosin light chain (MLC2) mRNA complete cds antibody; LC20 antibody; MGC3505 antibody; MLC 2 antibody; MLC-2C antibody; MLC2 antibody; MLY 9 antibody; MRLC1 antibody; MYL9 antibody; MYL9_HUMAN antibody; Myosin light chain 9 regulatory antibody; Myosin light polypeptide 9 regulatory antibody; myosin regulatory light chain 1 antibody; Myosin regulatory light chain 2 antibody; Myosin regulatory light chain 2 smooth muscle isoform antibody; Myosin regulatory light chain 9 antibody; Myosin regulatory light chain MRLC1 antibody; Myosin regulatory light polypeptide 9 antibody; Myosin RLC antibody; Myosin vascular smooth muscle light chain 2 antibody; MYRL2 antibody; OTTHUMP00000030857 antibody; smooth muscle isoform antibody

UniProt: P24844