Estrogen Receptor alpha Antikörper (pSer118)

Produktnummer ABIN7138414

Produktdetails anti-Estrogen Receptor alpha Antikörper

Target: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Bindungsspezifität: pSer118

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Estrogen Receptor alpha Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human, Affe, Maus

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of serine 118 (Q-L-S(p)-P-F) derived from Human Estrogen Receptor-a.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Estrogen Receptor alpha

Target: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Andere Bezeichnung: ESR1 (ESR1 Produkte)

Hintergrund:

Background:

Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.

Ramsauer VP, et al. (2003)J Biol Chem, 278(32): 30142-7.
Jepson S, et al. (2002)Oncogene, 21(49): 7524-32.
Ren Z, et al. (2002)J Biol Chem, 277(41): 38486-93.
Eppenberger-Castori S, et al. (2001)J Clin Oncol, 19(3): 645-56.

Aliases: 7*/654 isoform antibody, 7*/819 2 isoform antibody, 7*/822 isoform antibody, 8*/901 isoform antibody, 8*/941 isoform antibody, DKFZp686N23123 antibody, ER alpha antibody, ER antibody, ER-alpha antibody, Era antibody, ESR antibody, ESR1 antibody, ESR1_HUMAN antibody, ESRA antibody, Estradiol receptor antibody, Estrogen nuclear receptor alpha antibody, Estrogen receptor 1 antibody, Estrogen receptor alpha 3*,4,5,6,7*/822 isoform antibody, Estrogen receptor alpha antibody, Estrogen receptor alpha delta 3*,4,5,6,7*,8*/941 isoform antibody, Estrogen receptor alpha delta 3*,4,5,6,7*/819 2 isoform antibody, Estrogen receptor alpha delta 4 +49 isoform antibody, Estrogen receptor alpha delta 4*,5,6,7*/654 isoform antibody, Estrogen receptor alpha delta 4*,5,6,7,8*/901 isoform antibody, Estrogen receptor alpha E1 E2 1 2 antibody, Estrogen receptor alpha E1 N2 E2 1 2 antibody, Estrogen receptor antibody, ESTRR antibody, NR3A1 antibody, Nuclear receptor subfamily 3 group A member 1 antibody

UniProt: P03372

Pathways: Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly