CRY1 Antikörper

Produktnummer ABIN7138290

Der Kaninchen-Polyklonal Anti-CRY1-Antikörper wurde für WB und ELISA validiert. Er ist geeignet zum Nachweis von CRY1 in Proben aus Human. }

Kurzübersicht für CRY1 Antikörper (ABIN7138290)

Target: CRY1 (Cryptochrome 1 (Photolyase-Like) (CRY1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRY1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CRY1 Antikörper

Verwendungszweck: CRY1 Antibody

Kreuzreaktivität: Maus

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: Peptide sequence around aa.551~555 (S-Q-G-S-G) derived from Human CRY1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CRY1

Target: CRY1 (Cryptochrome 1 (Photolyase-Like) (CRY1))

Andere Bezeichnung: CRY1

Hintergrund:

Background:

Blue light-dependent regulator of the circadian feedback loop. Inhibits CLOCK|NPAS2-ARNTL E box-mediated transcription. Acts, in conjunction with CRY2, in maintaining period length and circadian rhythmicity. Has no photolyase activity. Capable of translocating circadian clock core proteins such as PER proteins to the nucleus. May inhibit CLOCK|NPAS2-ARNTL transcriptional activity through stabilizing the unphosphorylated form of ARNTL

Morioka N,et al. (2010) J Pharmacol Sci.113(3):234-45.
Fonseca F,et al. (2010) Mol Diagn Ther.14(3):171-8.
Stratmann M,et al.(2010) Genes Dev.24(12):1317-28.

Aliases: Cry1 antibody, CRY1_HUMAN antibody, Cryptochrome 1 (photolyase like) antibody, Cryptochrome 1 antibody, Cryptochrome-1 antibody, PHLL1 antibody, Photolyase 1 antibody, Photolyase-like antibody

UniProt: Q16526

Pathways: Response to Water Deprivation, Proton Transport