DAB1 Antikörper

Produktnummer ABIN7138126

Produktdetails anti-DAB1 Antikörper

Target: DAB1 (Disabled Homolog 1 (Drosophila) (DAB1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DAB1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: Peptide sequence around aa.230~234 (G-V-Y-D-V) derived from Human Dab1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC:1:50-1:100,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu DAB1

Target: DAB1 (Disabled Homolog 1 (Drosophila) (DAB1))

Andere Bezeichnung: DAB1 (DAB1 Produkte)

Hintergrund:

Background: The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.

Kelian Chen, et,al. (2003) J. Cell Sci , 117: 4527 - 4536.
Vera Strasser, et,al. (2004) Mol. Cell. Biol , 24: 1378 - 1386.
Izhar Ben-Shlomo, et,al. (2003) Sci. STKE , 2003: 9.
H. M. Kim, et,al. (2002) PNAS , 99: 4020.

Aliases: Dab 1 antibody, Dab reelin signal transducer 1 antibody, Dab, reelin signal transducer, homolog 1 (Drosophila) antibody, Dab1 antibody, DAB1_HUMAN antibody, Disabled homolog 1 antibody, Disabled homolog 1 Drosophila antibody, Scm antibody, Scr antibody, Scrambler antibody, Yot antibody, Yotari antibody

UniProt: O75553