ME1 Antikörper (AA 451-550)

Produktnummer ABIN709436

Der Kaninchen Polyklonal Anti-ME1-Antikörper wurde für WB, ELISA, IHC (p), IHC (fro), IF (cc) und IF (p) validiert. Er ist geeignet, ME1 in Proben von Ratte zu detektieren.

Kurzübersicht für ME1 Antikörper (AA 451-550) (ABIN709436)

Target: ME1 (Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ME1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-ME1 Antikörper

Bindungsspezifität: AA 451-550

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Malic enzyme 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu ME1

Target: ME1 (Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1))

Andere Bezeichnung: ME1

Hintergrund:

Synonyms: Cytosolic malic enzyme 1, HUMNDME, Malate dehydrogenase, Malic enzyme 1, Malic enzyme 1, NADP+ dependent, cytosolic, Malic enzyme 1, soluble, Malic enzyme, cytoplasmic, MES, NADP dependent malic enzyme, NADP ME, Pyruvic malic carboxylase.Cytosolic malic enzyme 1, HUMNDME, Malate dehydrogenase, Malic enzyme 1, Malic enzyme 1, NADP+ dependent, cytosolic, Malic enzyme 1, soluble, Malic enzyme, cytoplasmic, MES, NADP dependent malic enzyme, NADP ME, Pyruvic malic carboxylase.

Background: ME1 is a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet.

Gen-ID: 4199

Pathways: Regulation of Lipid Metabolism by PPARalpha