Lamin B Receptor Antikörper (AA 1-100) (Cy7)
Kurzübersicht für Lamin B Receptor Antikörper (AA 1-100) (Cy7) (ABIN709397)
Target
Alle Lamin B Receptor (LBR) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-100
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Spezifität
- The immunogen for this product has partial sequence similarity to SEPT8 and SEPT2
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Kreuzreaktivität
- Human, Maus
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Homologie
- Rat,Cow,Horse,Rabbit
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human Lamin B Receptor
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Isotyp
- IgG
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Applikationshinweise
- FCM 1:20-100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- Lamin B Receptor (LBR)
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Andere Bezeichnung
- Lamin B Receptor
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Hintergrund
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Synonyms: PHA, LMN2R, TDRD18, DHCR14B, Lamin-B receptor, Integral nuclear envelope inner membrane protein, LBR
Background: Lamins are nuclear membrane proteins that serve to maintain specific cellular functions, such as DNA replication and chromatin organization. Lamin B receptor (LBR) is an integral protein of the nuclear envelope inner membrane. It is phosphorylated by CDC2 protein kinase in mitosis when the inner nuclear membrane breaks down into vesicles that dissociate from the lamina and the chromatin. It is phosphorylated by different protein kinases in interphase when the membrane is associated with these structures. The cleavage of lamins results in nuclear disregulation and cell death.
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Gen-ID
- 3930
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UniProt
- Q14739
Target
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