Ceramide Synthase 2 (CERS2) (AA 230-261) Antikörper (FITC)

Details zu Produkt Nr. ABIN709338
Antigen
Epitop
AA 230-261
14
9
4
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
68
24
22
8
5
5
5
4
4
4
2
1
1
Wirt
Kaninchen
49
19
Klonalität
Polyklonal
Konjugat
FITC
3
3
3
3
3
3
3
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
46
14
12
7
5
2
1
1
1
1
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human Ceramide synthase 2
Isotyp IgG
Reinigung Purified by Protein A.
Antigen
Andere Bezeichnung Ceramide Synthase 2 (CERS2 Antibody Abstract)
Hintergrund

LASS2 (LAG1 homolog, ceramide synthase 2) has sequence similarity to yeast longevity assurance gene 1. It is thought to be involved in sphingolipid synthesis. Expression of LASS2 is transiently increased during the period of active myelination and is specifically localized to white matter tracts of the brain, including the Schwann cells of sciatic nerves suggesting that LASS2 is important for the synthesis of dihydroceramide used for synthesis of myelin sphingolipids. Expression of LASS2 in hepatocellular carcinoma cell lines suppresses the growth of cancer cells.

Subcellular location: Lumenal

Synonyms: L3, LASS2, SP260, TMSG1, Ceramide synthase 2, CerS2, LAG1 longevity assurance homolog 2, Tumor metastasis-suppressor gene 1 protein

Gen-ID 29956
UniProt Q96G23
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months