Ceramide Synthase 2 Antikörper (AA 201-300) (Biotin)

Produktnummer ABIN709333

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Ceramide Synthase 2 in WB, ELISA, IHC (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Maus und Ratte.

Kurzübersicht für Ceramide Synthase 2 Antikörper (AA 201-300) (Biotin) (ABIN709333)

Target: Ceramide Synthase 2 (CERS2)

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ceramide Synthase 2 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-Ceramide Synthase 2 Antikörper (Biotin)

Bindungsspezifität: AA 201-300

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Ceramide synthase 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu Ceramide Synthase 2

Target: Ceramide Synthase 2 (CERS2)

Andere Bezeichnung: Ceramide synthase 2

Hintergrund:

Synonyms: L3, LASS2, SP260, TMSG1, Ceramide synthase 2, CerS2, LAG1 longevity assurance homolog 2, Tumor metastasis-suppressor gene 1 protein

Background: LASS2 (LAG1 homolog, ceramide synthase 2) has sequence similarity to yeast longevity assurance gene 1. It is thought to be involved in sphingolipid synthesis. Expression of LASS2 is transiently increased during the period of active myelination and is specifically localized to white matter tracts of the brain, including the Schwann cells of sciatic nerves suggesting that LASS2 is important for the synthesis of dihydroceramide used for synthesis of myelin sphingolipids. Expression of LASS2 in hepatocellular carcinoma cell lines suppresses the growth of cancer cells.

Gen-ID: 29956

UniProt: Q96G23