TMEM123 Antikörper

Produktnummer ABIN7131392

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TMEM123 in ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TMEM123 Antikörper (ABIN7131392)

Target: TMEM123 (Transmembrane Protein 123 (TMEM123))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMEM123 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-TMEM123 Antikörper

Verwendungszweck: TMEM123 Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of Human TMEM123

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:  pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu TMEM123

Target: TMEM123 (Transmembrane Protein 123 (TMEM123))

Andere Bezeichnung: TMEM123

Hintergrund:

Background: This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.

Aliases: TMEM123 antibody, KCT3 antibody, PSEC0111 antibody, UNQ641/PRO1271 antibody, Porimin antibody, Keratinocytes-associated transmembrane protein 3 antibody, KCT-3 antibody, Pro-oncosis receptor inducing membrane injury antibody, Transmembrane protein 123 antibody

UniProt: Q8N131

Pathways: Regulation of Cell Size