PCP4 Antikörper

Produktnummer ABIN7130557

Produktdetails anti-PCP4 Antikörper

Target: PCP4 (Purkinje Cell Protein 4 (PCP4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCP4 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of Human PCP4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:5-1:20,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PCP4

Target: PCP4 (Purkinje Cell Protein 4 (PCP4))

Andere Bezeichnung: PCP4 (PCP4 Produkte)

Synonyme: PEP-19 antikoerper, P16Rimb19 antikoerper, Pcp-4 antikoerper, Pep19 antikoerper, PEPZ19 antikoerper, pep-19 antikoerper, Purkinje cell protein 4 antikoerper, PCP4 antikoerper, Pcp4 antikoerper

Hintergrund:

Background: PCP-4 (Purkinje cell protein 4), also known as PEP-19, is a calmodulin (CaM) regulatory protein that is highly expressed in neuronal cells. Through its IQ motif, PCP-4 mediates both the calcium-dependent binding properties of CaM and the rates of association and dissociation of calcium from the C-terminal domain of CaM. The IQ motif contains a serine residue which can be phosphorylated by all isoforms of protein kinase C (PKC). PCP-4 is implicated in uterine leiomyomas, as well as in neurodegenerative disorders such as Alzheimer's disease and Huntington's disease. Additionally, overexpression of PCP-4 is thought to play a role in cerebellar hypoplasia, a key feature of Down syndrome.

Aliases: Brain specific antigen PCP 4 antibody, Brain specific polypeptide PEP 19 antibody, Brain specific polypeptide PEP19 antibody, Brain-specific antigen PCP-4 antibody, Brain-specific polypeptide PEP-19 antibody, OTTHUMP00000109191 antibody, Pcp4 antibody, PCP4_HUMAN antibody, PEP19 antibody, Purkinje cell protein 4 antibody

UniProt: P48539