MCTS1 Antikörper
Kurzübersicht für MCTS1 Antikörper (ABIN7130206)
Target
Alle MCTS1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Human
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Aufreinigung
- Antigen affinity purification
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Immunogen
- Fusion protein of Human MCTS1
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Isotyp
- IgG
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Applikationshinweise
- ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:50-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MCTS1 (Malignant T Cell Amplified Sequence 1 (MCTS1))
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Andere Bezeichnung
- MCTS1
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Hintergrund
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Background: MCTS1 (malignant T cell amplified sequence 1), also known as MCT1, is a 181 amino acid protein that is ubiquitously expressed and localizes to the cytoplasm of cells. MCTS1 may play a role in cell cycle regulation by decreasing cell doubling time and by shortening the duration of G1 transit time and G1/S transition. The protein level of Cdk4 and Cdk6 kinases activity and cyclin D1 is enhanced by expression of MCTS1. As a translation enhancer, MCTS1 recruits DENR and binds to the cap complex of the 5'-terminus of mRNAs, subsequently altering the mRNA translation profile. MCTS1 promotes lymphoid tumor development and contributes to the pathogenesis and progression of breast cancer. MCTS1 positively regulates phosphorylation of ERK1 and ERK2.
Aliases: FLJ39637 antibody, Malignant T cell amplified sequence 1 antibody, Malignant T cell-amplified sequence 1 antibody, MCT 1 antibody, MCT-1 antibody, MCT1 antibody, MCTS 1 antibody, MCTS1 antibody, MCTS1_HUMAN antibody, Multiple copies T cell malignancies 1 antibody, Multiple copies T cell malignancies antibody, Multiple copies T-cell malignancies antibody, Oncogene MCT 1 antibody, Oncogene MCT1 antibody
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UniProt
- Q9ULC4
Target
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