DAZ4 Antikörper

Produktnummer ABIN7129152

Der Kaninchen Polyklonal Anti-DAZ4-Antikörper wurde für IHC und ELISA validiert. Er ist geeignet, DAZ4 in Proben von Human zu detektieren.

Kurzübersicht für DAZ4 Antikörper (ABIN7129152)

Target: DAZ4 (Deleted In Azoospermia 4 (DAZ4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DAZ4 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Produktdetails anti-DAZ4 Antikörper

Kreuzreaktivität: Human

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of Human DAZ4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA:1:500-1:5000, IHC:1:5-1:20,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu DAZ4

Target: DAZ4 (Deleted In Azoospermia 4 (DAZ4))

Andere Bezeichnung: DAZ4

Hintergrund:

Background: This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications, one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat, the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified, this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains two copies of the 10.8 kb repeat. Alternatively spliced transcript variants encoding different isoforms have been described.

Aliases: DAZ4Deleted in azoospermia protein 4 antibody

UniProt: Q86SG3