Rekombinanter SIRT5 Antikörper
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- Target Alle SIRT5 Antikörper anzeigen
- SIRT5 (Sirtuin 5 (SIRT5))
- Antikörpertyp
- Recombinant Antibody
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser SIRT5 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), ELISA
- Kreuzreaktivität
- Human
- Aufreinigung
- Affinity-chromatography
- Immunogen
- A synthesized peptide derived from human SIRT5
- Klon
- 9H12
- Isotyp
- IgG
- Top Product
- Discover our top product SIRT5 Primärantikörper
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anti-Sirtuin 5 (SIRT5) (AA 37-310) antibody
SIRT5 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Sirtuin 5 (SIRT5) antibodySIRT5 Reaktivität: Human, Ratte WB, IHC, FACS, IF, IHC (p) Wirt: Maus Monoclonal 2F1 unconjugated
anti-Sirtuin 5 (SIRT5) (AA 120-170) antibodySIRT5 Reaktivität: Human, Maus, Ratte WB, FACS, IHC (p), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Sirtuin 5 (SIRT5) (AA 263-292), (C-Term) antibodySIRT5 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB2111 unconjugated
anti-Sirtuin 5 (SIRT5) (Middle Region) antibodySIRT5 Reaktivität: Human, Maus, Rind (Kuh), Ziege, Kaninchen, Schwein WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Sirtuin 5 (SIRT5) (AA 37-310) antibodySIRT5 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Sirtuin 5 (SIRT5) (AA 60-212) antibodySIRT5 Reaktivität: Human IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Sirtuin 5 (SIRT5) (AA 184-233) antibodySIRT5 Reaktivität: Human, Maus, Schwein WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Sirtuin 5 (SIRT5) (AA 1-310) antibodySIRT5 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Sirtuin 5 (SIRT5) (C-Term) antibodySIRT5 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Ziege, Kaninchen, Meerschweinchen, Hund, Pferd, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Recommended dilution: IHC:1:50-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- SIRT5 (Sirtuin 5 (SIRT5))
- Andere Bezeichnung
- SIRT5 (SIRT5 Produkte)
- Hintergrund
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Background: NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins (PubMed:21908771, PubMed:22076378, PubMed:24703693). Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting (PubMed:22076378, PubMed:24703693). Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species (PubMed:24140062). Modulates ketogenesis through the desuccinylation and activation of HMGCS2 (By similarity). Has weak NAD-dependent protein deacetylase activity, however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro such as UOX.
Aliases: NAD-dependent protein deacylase sirtuin-5, mitochondrial (EC 3.5.1.-) (Regulatory protein SIR2 homolog 5) (SIR2-like protein 5), SIRT5, SIR2L5
- UniProt
- Q9NXA8
- Pathways
- SARS-CoV-2 Protein Interaktom
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