Rekombinanter METAP2 Antikörper
Kurzübersicht für Rekombinanter METAP2 Antikörper (ABIN7127617)
Target
Alle METAP2 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Kreuzreaktivität
- Human
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Aufreinigung
- Affinity-chromatography
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Immunogen
- A synthesized peptide derived from human Methionine Aminopeptidase 2
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: IHC:1:50-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- METAP2 (Methionyl Aminopeptidase 2 (METAP2))
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Andere Bezeichnung
- METAP2
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Hintergrund
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Background: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). The catalytic activity of human METAP2 toward Met-Val peptides is consistently two orders of magnitude higher than that of METAP1, suggesting that it is responsible for processing proteins containing N-terminal Met-Val and Met-Thr sequences in vivo.
Aliases: Methionine aminopeptidase 2 (MAP 2) (MetAP 2) (EC 3.4.11.18) (Initiation factor 2-associated 67 kDa glycoprotein) (p67) (p67eIF2) (Peptidase M), METAP2, MNPEP P67EIF2
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UniProt
- P50579
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Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
Target
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