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Rekombinanter Menin Antikörper

MEN1 Reaktivität: Human WB, ELISA Wirt: Kaninchen Monoclonal 8G11 unconjugated Recombinant Antibody
Produktnummer ABIN7127614
  • Target Alle Menin (MEN1) Antikörper anzeigen
    Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))
    Antikörpertyp
    Recombinant Antibody
    Reaktivität
    • 77
    • 32
    • 24
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 69
    • 6
    • 2
    • 1
    Kaninchen
    Klonalität
    • 71
    • 7
    Monoklonal
    Konjugat
    • 39
    • 7
    • 7
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Menin Antikörper ist unkonjugiert
    Applikation
    • 57
    • 38
    • 23
    • 18
    • 13
    • 13
    • 11
    • 8
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    Affinity-chromatography
    Immunogen
    A synthesized peptide derived from human Menin
    Klon
    8G11
    Isotyp
    IgG
    Top Product
    Discover our top product MEN1 Primärantikörper
  • Applikationshinweise
    Recommended dilution: WB:1:500-1:5000,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))
    Andere Bezeichnung
    MEN1 (MEN1 Produkte)
    Synonyme
    MEAI antikoerper, SCG2 antikoerper, menin antikoerper, meai antikoerper, scg2 antikoerper, AW045611 antikoerper, menin 1 antikoerper, menin 1 L homeolog antikoerper, multiple endocrine neoplasia I antikoerper, multiple endocrine neoplasia 1 antikoerper, MEN1 antikoerper, men1 antikoerper, men1.L antikoerper, Men1 antikoerper
    Hintergrund

    Background: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression (By similarity). May be involved in DNA repair.

    Aliases: Menin, MEN1, SCG2

    UniProt
    O00255
    Pathways
    Chromatin Binding, Positive Regulation of Endopeptidase Activity
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