Rekombinanter ILK Antikörper

Produktnummer ABIN7127572

Produktdetails anti-ILK Antikörper

Target: ILK (Integrin-Linked Kinase (ILK))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser ILK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Kreuzreaktivität: Human, Maus

Aufreinigung: Affinity-chromatography

Immunogen: A synthesized peptide derived from human ILK

Klon: 6A5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IF:1:20-1:200, IP:1:200-1:1000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ILK

Target: ILK (Integrin-Linked Kinase (ILK))

Andere Bezeichnung: ILK (ILK Produkte)

Synonyme: CG10504 antikoerper, CT29478 antikoerper, DmILK antikoerper, Dmel\\CG10504 antikoerper, ILK antikoerper, ilk antikoerper, l(3)78Ca antikoerper, p59 antikoerper, AA511515 antikoerper, ESTM24 antikoerper, zgc:65842 antikoerper, ILK-1 antikoerper, ILK-2 antikoerper, P59 antikoerper, p59ILK antikoerper, Integrin linked kinase antikoerper, integrin linked kinase antikoerper, integrin linked kinase S homeolog antikoerper, integrin-linked protein kinase antikoerper, integrin-linked kinase antikoerper, Ilk antikoerper, ILK antikoerper, ilk.S antikoerper, CpipJ_CPIJ016644 antikoerper, Bm1_20815 antikoerper, Tsp_07213 antikoerper, Tsp_07224 antikoerper, Tsp_15354 antikoerper, ilk antikoerper

Hintergrund:

Background: Receptor-proximal protein kinase regulating integrin-mediated signal transduction (PubMed:8538749, PubMed:9736715). May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B (PubMed:8538749, PubMed:9736715).

Aliases: Integrin-linked protein kinase (EC 2.7.11.1) (59 kDa serine/threonine-protein kinase) (ILK-1) (ILK-2) (p59ILK), ILK, ILK1 ILK2

UniProt: Q13418

Pathways: Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration