Rekombinanter HNRNPK Antikörper
Kurzübersicht für Rekombinanter HNRNPK Antikörper (ABIN7127548)
Target
Alle HNRNPK Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- HNRNPK Recombinant Monoclonal Antibody
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Aufreinigung
- Affinity-chromatography
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Immunogen
- A synthesized peptide derived from human HNRNPK
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Isotyp
- IgG
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anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (AA 1-280) antibody
HNRNPK Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) antibodyHNRNPK Reaktivität: Human WB, IF, ICC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) antibodyKD Validated HNRNPK Reaktivität: Human WB, FACS Wirt: Kaninchen Monoclonal 23GB4825 unconjugated Recombinant Antibody
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (AA 200-250) antibodyHNRNPK Reaktivität: Human, Maus, Ratte, Affe, Opossum WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (AA 1-50) antibodyHNRNPK Reaktivität: Human, Maus, Ratte, Affe, Opossum WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (AA 380-430) antibodyHNRNPK Reaktivität: Human, Maus, Ratte, Affe, Opossum IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (AA 1-463) antibodyHNRNPK Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) antibodyHNRNPK Reaktivität: Human, Maus, Ratte, Rind (Kuh), Xenopus laevis, Hamster WB, IHC, ELISA, IF, IP, ICC, FACS, ChIP Wirt: Maus Monoclonal 3C2 unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (pSer284) antibodyHNRNPK Reaktivität: Human, Maus WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) antibodyHNRNPK Reaktivität: Human, Maus, Ratte, Kaninchen, Huhn, Hund, Affe, Ziege, Pferd WB, IHC, IHC (p) Wirt: Maus Monoclonal F45 P9 C7 unconjugated
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Applikationshinweise
- WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200, IP:1:200-1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))
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Andere Bezeichnung
- HNRNPK
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Hintergrund
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Background: One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction (By similarity). As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21 (lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest.
Aliases: Heterogeneous nuclear ribonucleoprotein K, hnRNP K, Transformation up-regulated nuclear protein, TUNP, HNRNPK, HNRPK
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UniProt
- P61978
Target
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