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Rekombinanter CXCR4 Antikörper

Der Kaninchen Monoklonal Anti-CXCR4-Antikörper wurde für ELISA und IF validiert. Er ist geeignet, CXCR4 in Proben von Human zu detektieren.
Produktnummer ABIN7127439

Kurzübersicht für Rekombinanter CXCR4 Antikörper (ABIN7127439)

Target

Alle CXCR4 Antikörper anzeigen
CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Antikörpertyp

Recombinant Antibody

Reaktivität

  • 163
  • 91
  • 66
  • 21
  • 11
  • 10
  • 10
  • 6
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 133
  • 36
  • 12
  • 9
  • 2
  • 1
  • 1
  • 1
Kaninchen

Klonalität

  • 141
  • 52
  • 1
Monoklonal

Konjugat

  • 117
  • 9
  • 8
  • 7
  • 7
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CXCR4 Antikörper ist unkonjugiert

Applikation

  • 129
  • 66
  • 55
  • 53
  • 35
  • 29
  • 26
  • 26
  • 25
  • 25
  • 9
  • 6
  • 5
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
ELISA, Immunofluorescence (IF)

Klon

2F10
  • Kreuzreaktivität

    Human

    Aufreinigung

    Affinity-chromatography

    Immunogen

    A synthesized peptide derived from human CXCR4

    Isotyp

    IgG
  • Applikationshinweise

    Recommended dilution: IF:1:20-1:200,

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

    Andere Bezeichnung

    CXCR4

    Hintergrund

    Background: Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin, leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival.

    Aliases: C-X-C chemokine receptor type 4 (CXC-R4) (CXCR-4) (FB22) (Fusin) (HM89) (LCR1) (Leukocyte-derived seven transmembrane domain receptor) (LESTR) (Lipopolysaccharide-associated protein 3) (LAP-3) (LPS-associated protein 3) (NPYRL) (Stromal cell-derived factor 1 receptor) (SDF-1 receptor) (CD antigen CD184), CXCR4

    UniProt

    P61073

    Pathways

    Regulation of Cell Size, CXCR4-mediated Signaling Events
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