BPIFB1 Antikörper

Produktnummer ABIN7127157

Produktdetails anti-BPIFB1 Antikörper

Target: BPIFB1 (BPI Fold Containing Family B, Member 1 (BPIFB1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BPIFB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Spezifität: The upper respiratory tract is the main place of entry for pathogens to invade the body, and early recognition of bacterial products in this region is crucial for host defense. Palate lung nasal epithelial clone PLUNC (or LUNX) is an airway specific secretory protein that is expressed in epithelial tissues and submucosal glands of the oral cavity and upper respiratory tract of humans, mice, rats and cows. PLUNC binds to lipopolysaccharide (LPS) in nasal lavage fluid (NLF) which points to its role in the inflammatory response of the upper airways after exposure to irritants. Decreased levels of PLUNC occur in the NLF of smokers and people who have been exposed to reactive epoxy chemicals, indicating that long-term exposure to airway irritants impairs the production of PLUNC in the upper respiratory tract. Abnormal expression of PLUNC may influence susceptibility to nasopharyngeal carcinoma in the Chinese population.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human BPIFB1 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Known_Application: ELISA (For coating, order antibody without BSA), Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Human lung tissue. HeLa cells.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu BPIFB1

Target: BPIFB1 (BPI Fold Containing Family B, Member 1 (BPIFB1))

Andere Bezeichnung: BPIFB1 (BPIFB1 Produkte)

Synonyme: C20orf114 antikoerper, LPLUNC1 antikoerper, Lplunc1 antikoerper, C13H20orf114 antikoerper, RGD1563047 antikoerper, BPI fold containing family B member 1 antikoerper, BPI fold containing family B, member 1 antikoerper, BPIFB1 antikoerper, Bpifb1 antikoerper

Hintergrund: BPI fold containing family B, member 1, Long palate, lung and nasal epithelium carcinoma associated protein 1 (Lplunc1), lung and nasal epithelium carcinoma-associated protein 1, VEMSGP, Von Ebner minor salivary gland protein,L-PLUNC
Cellular localisation: Secreted

Molekulargewicht: 25kDa

Gen-ID: 92747, 65551

UniProt: Q8TDL5