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CD5L Antikörper (AA 269-366)

Der Maus Monoklonal Anti-CD5L-Antikörper wurde für WB, IF, FACS und IHC (f) validiert. Er ist geeignet, CD5L in Proben von Human zu detektieren.
Produktnummer ABIN7127146

Kurzübersicht für CD5L Antikörper (AA 269-366) (ABIN7127146)

Target

Alle CD5L Antikörper anzeigen
CD5L (CD5 Molecule-Like (CD5L))

Reaktivität

  • 41
  • 35
  • 26
Human

Wirt

  • 73
  • 5
  • 1
Maus

Klonalität

  • 72
  • 4
  • 2
Monoklonal

Konjugat

  • 34
  • 15
  • 8
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CD5L Antikörper ist unkonjugiert

Applikation

  • 53
  • 26
  • 21
  • 16
  • 13
  • 13
  • 12
  • 8
  • 6
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
  • Bindungsspezifität

    • 15
    • 9
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 269-366

    Spezifität

    CD5L (CD5 Molecule-like), also known as API6, PRO229, Sp or SP-ALPHA, is a 347 amino acid secreted protein that belongs to the scavenger receptor cysteine-rich (SRCR) family of leukocyte regulating proteins. Expressed in bone marrow, spleen, thymus, lymph node and fetal liver, CD5L is thought to be involved in regulating the immune system via binding to peripheral monocytes and mediating their activation and overall survival. CD5L has three cysteine-rich domains and, in addition to its role in the immune system, may function to inhibit apoptosis and promote macrophage survival.

    Kreuzreaktivität (Details)

    Human.

    Aufreinigung

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    Immunogen

    Recombinant fragment of human CD5 protein (around aa 269-366) (exact sequence is proprietary)

    Isotyp

    IgG2b
  • Applikationshinweise

    Known_Application: Flow Cytometry (1-2 μg/million cells), Western Blot (1-2 μg/mL), Immunofluorescence (1-2 μg/million cells),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: 293T, Ramos, or MOLT-4 cells. Tonsil or Lymph Node.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1.0 mg/mL

    Buffer

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    Konservierungsmittel

    Azide free

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    Haltbarkeit

    24 months
  • Target

    CD5L (CD5 Molecule-Like (CD5L))

    Andere Bezeichnung

    CD5L

    Hintergrund

    AAC-11, AIM, API6, APOPTOSIS INHIBITOR 6, APOPTOSIS INHIBITOR OF MACROPHAGES, CD5 antigen like (scavenger receptor cysteine rich family), CD5 antigen-like, CT-2, Highly similar to ANTIGEN WC1.1 [Bos taurus], IgM-associated peptide, Pdp, PRO229, SCAVENGER RECEPTOR CYSTEINE-RICH FAMILY, SP-alpha, Spalpha,CD5L / CD5LG / CD5 Ligand
    Cellular localisation: Secreted.

    Molekulargewicht

    38kDa

    Gen-ID

    922, 134035

    UniProt

    O43866
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