Rekombinanter Calretinin Antikörper (AA 23-242)

Produktnummer ABIN7127074

Der Kaninchen Monoklonal Anti-Calretinin-Antikörper wurde für IHC (f) validiert. Er ist geeignet, Calretinin in Proben von Human zu detektieren.

Kurzübersicht für Rekombinanter Calretinin Antikörper (AA 23-242) (ABIN7127074)

Target: Calretinin (CALB2) (Calbindin 2 (CALB2))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Calretinin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Produktdetails anti-Calretinin Antikörper

Bindungsspezifität: AA 23-242

Spezifität: It recognizes a protein of about 29 kDa, which is identified as Calretinin (also known as Calbindin 2). Calretinin is a vitamin D-dependent calcium-binding protein involved in calcium signaling. It is present in subsets of neurons throughout the brain and spinal chord, including sensory ganglia. Antibody to calretinin is useful in differentiating mesothelioma from adenocarcinomas of the lung. It also aids in differentiating adrenal cortical neoplasms from pheochromocytomas.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant human Calretinin (Calbindin 2) protein fragment (around aa23-242) (exact sequence is proprietary)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Human brain, testis or mesothelioma tissue.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu Calretinin

Target: Calretinin (CALB2) (Calbindin 2 (CALB2))

Andere Bezeichnung: CALB2

Hintergrund: 29 kDa calbindin, CAB29, CAL2, CALB2, Calbindin 2, Calbindin D29K, Calretinin, CR,Calretinin / Calbindin 2 (Mesothelioma Marker)
Cellular localisation: Cytoplasm. Nucleus.

Molekulargewicht: 29kDa

Gen-ID: 794, 106857

UniProt: P22676