Rekombinanter SELPLG Antikörper
Kurzübersicht für Rekombinanter SELPLG Antikörper (ABIN7126929)
Target
Alle SELPLG Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- CD162 glycoprotein functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response.
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Kreuzreaktivität (Details)
- Human.
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Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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Immunogen
- Recombinant full-length human SELPLG (CD162) protein
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Isotyp
- IgG1
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Applikationshinweise
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Known_Application: ELISA (For coating, order antibody without BSA),Optimal dilution for a specific application should be determined.
Positive_Control: Jurkat cells. Tonsil or Spleen.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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Haltbarkeit
- 24 months
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- SELPLG (Selectin P Ligand (SELPLG))
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Andere Bezeichnung
- SELPLG
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Hintergrund
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CD162, CLA, Cutaneous lymphocyte associated antigen, P-selectin glycoprotein ligand 1, PSGL1, Selectin P ligand, SELPLG,CD162 (Selectin P Ligand)
Cellular localisation: Cell Surface -
Molekulargewicht
- 43-120kDa
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Gen-ID
- 6404, 591014
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UniProt
- Q14242
Target
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