BCL2L2 Antikörper

Produktnummer ABIN7126898

Dieser Maus Monoklonal Antikörper erkennt spezifisch BCL2L2 in IP, IF und FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für BCL2L2 Antikörper (ABIN7126898)

Target: BCL2L2 (BCL2-Like 2 (BCL2L2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BCL2L2 Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-BCL2L2 Antikörper

Spezifität: This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant human full-length BCL2L2 protein

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise:

Known_Application: Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Positive_Control: PC-3, HEK293, HePG2, MCF-7 or U87 cells.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu BCL2L2

Target: BCL2L2 (BCL2-Like 2 (BCL2L2))

Andere Bezeichnung: BCL2L2

Hintergrund: BCL-W, BCL2-L-2, BCLW, KIAA0271, PPP1R51,BCL2-like 2 (BCL2L2) / BCL-W
Cellular localisation: Cytoplasm. Mitochondrion membrane.

Molekulargewicht: 22-30kDa

Gen-ID: 599, 410026

UniProt: Q92843