TRIM27 Antikörper

Produktnummer ABIN7126897

Produktdetails anti-TRIM27 Antikörper

Target: TRIM27 (Tripartite Motif Containing 27 (TRIM27))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TRIM27 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Flow Cytometry (FACS)

Spezifität: Defects in TRIM27 are a cause of thyroid papillary carcinoma (TPC) [MIM:188550]. TPC is a common tumor of the thyroid that typically arises as an irregular, solid or cystic mass from otherwise normal thyroid tissue. Papillary carcinomas are malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. Note=A chromosomal aberration involving TRIM27/RFP is found in thyroid papillary carcinomas. Translocation t(6,10)(p21.3,q11.2) with RET. The translocation generates TRIM27/RET and delta TRIM27/RET oncogenes.

Kreuzreaktivität (Details): Human. Predicted to react with Mouse and Rat.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human TRIM27 protein

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL),Optimal dilution for a specific application should be determined.

Positive_Control: HeLa, U87 or Raji cells.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu TRIM27

Target: TRIM27 (Tripartite Motif Containing 27 (TRIM27))

Andere Bezeichnung: TRIM27 (TRIM27 Produkte)

Synonyme: RFP antikoerper, RNF76 antikoerper, AW538890 antikoerper, Gm19403 antikoerper, Rfp antikoerper, TRIM27 antikoerper, Rfp1 antikoerper, tripartite motif containing 27 antikoerper, tripartite motif-containing 27 antikoerper, TRIM27 antikoerper, Trim27 antikoerper

Hintergrund: AW538890, DAAP-182E11.3, MGC189472, Ret finger protein, RFP transforming protein, Rfp1, RING finger protein 76, RNF76, Tripartite motif-containing protein 27, Zinc finger protein RFP,TRIM27
Cellular localisation: Nucleus. Cytoplasm. Nucleus > PML body. Nuclear or cytoplasmic depending on the cell type (By similarity). Colocalized with PML and EIF3S6 in nuclear bodies.

Molekulargewicht: 58.49kDa

Gen-ID: 5987, 440382

UniProt: P14373