OVOL2 Antikörper

Produktnummer ABIN7126865

Dieses Maus Monoklonal-Antikörper erkennt spezifisch OVOL2 in IF und FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für OVOL2 Antikörper (ABIN7126865)

Target: OVOL2 (Ovo-Like 2 (OVOL2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser OVOL2 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-OVOL2 Antikörper

Spezifität: The ATF/CREB family consists of a series of transcription factors that function by binding to the cAMP responsive element (CRE) palindromic octanucleotide, TGACCTCA. The best characterized members of this gene family include CREB-1, CREB-2 (also designated ATF-4), CRE-BPa, LZIP (also designated CREB-3 and Luman), CREM-2, ATF-1, ATF-2, ATF-3, ATF-5, ATF-6 and ATF-7. These transcription factors share terminal leucine zipper dimerization and basic DNA binding domains and are highly variable in their N-termini. Although each of the ATF/ CREB proteins bind CREs in their homodimeric form, they can also bind as heterodimers, both within the ATF/CREB family and with members of the AP-1 transcription factor family. Protein kinase A- mediated CREB phosphorylation induces association with a nuclear protein designated CBP (CREB-binding protein), which may represent a CREB coactivator. CRE-BPa is a nuclear protein that binds DNA as a homodimer but can also form a heterodimer with ATF-2 or Jun.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human OVOL2 protein

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

Known_Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL),Optimal dilution for a specific application should be determined.

Positive_Control: HeLa, U87 or K562 cells.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu OVOL2

Target: OVOL2 (Ovo-Like 2 (OVOL2))

Andere Bezeichnung: OVOL2

Hintergrund: BA504H3.3, hOvo2, Ovo like 2, ovo-like zinc finger 2 (OVOL2), Transcription factor Ovo-like 2, Zinc finger protein 339 (ZNF339),OVOL2 / CRE-BPa
Cellular localisation: Nucleus.

Molekulargewicht: 69.1kDa

Gen-ID: 58495, 437075

UniProt: Q9BRP0

Pathways: Tube Formation